The Fulton State Hospital project will replace aging facilities with a state-of-the-art mental hospital that will be safer and more conducive to modern treatment. In 2014, Missouri Governor Jay Nixon announced the selection of Parsons Brinckerhoff, a global consulting firm with offices in St. Louis, as the lead design firm for the Fulton State Hospital project.

The new Fulton State Hospital campus will be constructed on a 55-acre plot of land which has been home to the hospital since its inception in 1851. The new hospital will include six living areas with 50 beds each, for a total of 300 beds. Construction of the facility is slated to begin in the spring of 2015 and be completed in 2018.